Dynactin 3 (p22) (Dctn3) (C-Term) Peptide
Dctn3
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all DCTN3 (Dctn3) products
- DCTN3 (Dctn3) (Dynactin 3 (p22) (Dctn3))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- ARLQRLAQIH IQQQDQCVEI TEESKALLEE YNKTTMLLSK QFVQWDELLC
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-DCTN3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- DCTN3 (Dctn3) (Dynactin 3 (p22) (Dctn3))
- Synonyms
- zgc:92471 Peptide, wu:fc38g10 Peptide, p24 Peptide, NV12799 Peptide, DCTN-22 Peptide, DCTN22 Peptide, dynactin 3 (p22) Peptide, dynactin subunit 3 Peptide, dynactin 3 Peptide, dctn3 Peptide, LOC658790 Peptide, Dctn3 Peptide, DCTN3 Peptide
- Background
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This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing of this gene generates 2 transcript variants.
Alias Symbols: DCTN-22, DCTN22, MGC111190
Protein Interaction Partner: ATXN1,DCTN1,PBX2
Protein Size: 186 - Molecular Weight
- 20 kDa
- Gene ID
- 11258
- NCBI Accession
- NM_001248, NP_001239
- UniProt
- O75355
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