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Death Effector Domain Containing 2 (DEDD2) (Middle Region) Peptide

DEDD2 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN975717
  • Target See all DEDD2 products
    DEDD2 (Death Effector Domain Containing 2 (DEDD2))
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 1
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    PQQQSEPARP SSEGKVTCDI RLRVRAEYCE HGPALEQGVA SRRPQALARQ
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-DEDD2 Antibody(ARP52558_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    DEDD2 (Death Effector Domain Containing 2 (DEDD2))
    Synonyms
    FLAME-3 Peptide, MGC145883 Peptide, 2410050E11Rik Peptide, DEDD2 Peptide, death effector domain containing 2 Peptide, death effector domain containing 2 L homeolog Peptide, death effector domain-containing DNA binding protein 2 Peptide, DEDD2 Peptide, dedd2.L Peptide, dedd2 Peptide, Dedd2 Peptide
    Background
    DEDD2 may play a critical role in death receptor-induced apoptosis and may target CASP8 and CASP10 to the nucleus. DEDD2 may regulate degradation of intermediate filaments during apoptosis. DEDD2 may play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3.

    Alias Symbols: FLAME-3

    Protein Interaction Partner: CASP10,CASP8,CFLAR,DEDD,DEDD2,GTF3C3,CASP10,CASP8,CFLAR,DEDD,DEDD2,GTF3C3

    Protein Size: 326
    Molecular Weight
    36 kDa
    Gene ID
    162989
    NCBI Accession
    NM_133328, NP_579874
    UniProt
    Q8WXF8
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