DiGeorge Syndrome Critical Region Gene 8 (DGCR8) (N-Term) Peptide
DGCR8
Reactivity: Human
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN975746
Quick Overview for DiGeorge Syndrome Critical Region Gene 8 (DGCR8) (N-Term) Peptide (ABIN975746)
Target
DGCR8
(DiGeorge Syndrome Critical Region Gene 8 (DGCR8))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein Region
- N-Term
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-DGCR8 antibody (Catalog #: ARP40984_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- DGCR8 (DiGeorge Syndrome Critical Region Gene 8 (DGCR8))
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Background
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DGCR8 contains 2 DRBM (double-stranded RNA-binding) domains and 1 WW domain. It may play a part in the etiology of the velocardiofacial/DiGeorge syndrome (VCFS/DGS), a developmental disorder characterized by structural and functional palate anomalies, conotruncal cardiac malformations, immunodeficiency, hypocalcemia, and typical facial anomalies.
Alias Symbols: C22orf12, DGCRK6, Gy1, pasha
Protein Interaction Partner: RNASEN,RNASEN,RNASEN
Protein Size: 773 -
Molecular Weight
- 85 kDa
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Gene ID
- 54487
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NCBI Accession
- NM_022720, NP_073557
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UniProt
- Q8WYQ5
Target
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