DiGeorge Syndrome Critical Region Gene 8 (DGCR8) (Middle Region) Peptide
DGCR8
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all DGCR8 products
- DGCR8 (DiGeorge Syndrome Critical Region Gene 8 (DGCR8))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- TEEKYGGDSD HPSDGETSVQ PMMTKIKTVL KSRGRPPTEP LPDGWIMTFH
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-DGCR8 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- DGCR8 (DiGeorge Syndrome Critical Region Gene 8 (DGCR8))
- Synonyms
- MGC78846 Peptide, DGCR8 Peptide, gy1 Peptide, dgcrk6 Peptide, C22orf12 Peptide, DGCRK6 Peptide, Gy1 Peptide, pasha Peptide, D16H22S1742E Peptide, D16H22S788E Peptide, D16Wis2 Peptide, N41 Peptide, Vo59c07 Peptide, si:ch211-106a19.4 Peptide, wu:fc23f08 Peptide, wu:fc38f06 Peptide, DGCR8 microprocessor complex subunit L homeolog Peptide, DiGeorge syndrome critical region gene 8 Peptide, DGCR8 microprocessor complex subunit Peptide, DGCR8, microprocessor complex subunit Peptide, microRNA 3618 Peptide, dgcr8.L Peptide, DGCR8 Peptide, dgcr8 Peptide, Dgcr8 Peptide, MIR3618 Peptide
- Background
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This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants.
Alias Symbols: DGCR8,C22orf12, DGCRK6,LP4941,
Protein Size: 773 - Gene ID
- 54487
- NCBI Accession
- NP_073557
- UniProt
- Q8WYQ5
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