Dynamin 1 (DNM1) (Middle Region) Peptide
DNM1
Reactivity: Human
Host: Synthetic
BP, IHC, WB
Catalog No. ABIN975933
$160.46
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100 μg
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Quick Overview for Dynamin 1 (DNM1) (Middle Region) Peptide (ABIN975933)
Target
Dynamin 1 (DNM1)
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-DNM1 antibody (Catalog #: ARP51787_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Dynamin 1 (DNM1)
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Background
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DNM1 is a member of the dynamin subfamily of GTP-binding proteins. The protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described.This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described.
Alias Symbols: DNM
Protein Interaction Partner: AMPH,AP2A2,ASB13,BIN1,CABIN1,CAV1,CDK5,CLIC3,CLIC4,CTTN,DNM1,DNMBP,EPS15,FNBP1,GNB2L1,GRB2,GRIN1,GRIN2D,ITSN1,KIAA1377,MED31,MOBKL3,NCK1,NCK2,NME2,PACSIN1,PACSIN3,PFN2,PIAS1,PIK3R1,PIN4,PLCG1,PRKCA,PRNP,SH3GL1,SH3GL2,SH3GL3,SNAP25,SNX9,SRC,TIMM50,AMPH,ASB13,CABIN1,CLINT1,DNM1,DNMBP,DYRK1A,Eps15,FER,FNBP1,GRB2,KIAA1377,MAP3K10,MED31,NCK1,PACSIN1,PACSIN2,PACSIN3,PIN4,SH3GL1,SH3GL2,SH3GL3,SH3GLB1,UBASH3A
Protein Size: 851 -
Molecular Weight
- 95 kDa
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Gene ID
- 1759
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NCBI Accession
- NM_004408, NP_004399
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UniProt
- P39053
Target
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