DNA-Damage Regulated Autophagy Modulator 1 (DRAM1) (N-Term) Peptide
DRAM1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN975995
$160.46
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100 μg
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United States
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Quick Overview for DNA-Damage Regulated Autophagy Modulator 1 (DRAM1) (N-Term) Peptide (ABIN975995)
Target
DRAM (DRAM1)
(DNA-Damage Regulated Autophagy Modulator 1 (DRAM1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- TMYTRYKIVQ KQNQTCYFST PVFNLVSLVL GLVGCFGMGI VANFQELAVP
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-DRAM Antibody(ARP58891_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- DRAM (DRAM1) (DNA-Damage Regulated Autophagy Modulator 1 (DRAM1))
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Background
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This gene is regulated as part of the p53 tumor suppressor pathway. The gene encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this gene is associated with various tumors. This gene has a pseudogene on chromosome 4.
Alias Symbols: DRAM, FLJ11259
Protein Size: 238 -
Molecular Weight
- 26 kDa
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Gene ID
- 55332
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NCBI Accession
- NM_018370, NP_060840
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UniProt
- Q8N682
Target
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