Epithelial Splicing Regulatory Protein 2 (ESRP2) (C-Term) Peptide
ESRP2
Reactivity: Mouse
Host: Synthetic
BP, WB
Catalog No. ABIN976446
Quick Overview for Epithelial Splicing Regulatory Protein 2 (ESRP2) (C-Term) Peptide (ABIN976446)
Target
ESRP2
(Epithelial Splicing Regulatory Protein 2 (ESRP2))
Origin
Mouse
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- LLPAARVPAA ATPLAYYPGP ATQLYMNYTA YYPSPPVSPT TVGYLTTPPT
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-Esrp2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ESRP2 (Epithelial Splicing Regulatory Protein 2 (ESRP2))
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Background
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Esrp2 is an mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. It specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. It also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). It acts by directly binding specific sequences in mRNAs and binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2.
Alias Symbols: 9530027K23Rik, Rbm35b
Protein Size: 717 -
Molecular Weight
- 77 kDa
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Gene ID
- 77411
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NCBI Accession
- NM_176838, NP_789808
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UniProt
- Q8K0G8
Target
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