Coagulation Factor VII (F7) (Middle Region) Peptide
F7
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN976554
$160.46
Plus shipping costs $50.00
100 μg
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United States
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Quick Overview for Coagulation Factor VII (F7) (Middle Region) Peptide (ABIN976554)
Target
Factor VII (F7)
(Coagulation Factor VII (F7))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- RCHEGYSLLA DGVSCTPTVE YPCGKIPILE KRNASKPQGR IVGGKVCPKG
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-F7 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Factor VII (F7) (Coagulation Factor VII (F7))
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Background
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This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Alternative splicing of this gene results in 2 transcripts. Defects in this gene can cause coagulopathy.
Alias Symbols: SPCA
Protein Size: 466 -
Molecular Weight
- 28 kDa
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Gene ID
- 2155
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NCBI Accession
- NM_000131, NP_000122
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UniProt
- P08709
Target
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