Feline Sarcoma Oncogene (FES) (N-Term) Peptide
FES
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN976813
Quick Overview for Feline Sarcoma Oncogene (FES) (N-Term) Peptide (ABIN976813)
Target
FES
(Feline Sarcoma Oncogene (FES))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- EGMRKWMAQR VKSDREYAGL LHHMSLQDSG GQSRAISPDS PISQTHSQDI
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-FES Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- FES (Feline Sarcoma Oncogene (FES))
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Background
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FES is the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. FES has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis.
Alias Symbols: FPS
Protein Interaction Partner: BCAR1,BCR,CSF2RB,DOK1,DPYSL5,FES,HSH2D,IL4R,IRS1,IRS2,JAK1,JAK2,JAK3,PIK3R1,PLXNA1,RASA1,RASA3,STAT3,BCAR1,BCR,FKBP4,FKBP5,HSH2D,HSP90AA1,HSPA4,PIK3R1,PPID,PSMD13,PTGES3,STAT3
Protein Size: 764 -
Molecular Weight
- 84 kDa
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Gene ID
- 2242
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NCBI Accession
- NM_001143783, NP_001137255
Target
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