Feline Sarcoma Oncogene (FES) Peptide
FES
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all FES products
- FES (Feline Sarcoma Oncogene (FES))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-FES antibody (Catalog #: ARP54608_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- FES (Feline Sarcoma Oncogene (FES))
- Synonyms
- FPS Peptide, RGD1564385 Peptide, AI586313 Peptide, BB137047 Peptide, c-fes Peptide, FES Peptide, c-fps Peptide, FES proto-oncogene, tyrosine kinase Peptide, feline sarcoma oncogene Peptide, FES Peptide, Fes Peptide, fes Peptide
- Background
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FES is the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. FES has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis. This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis. A truncated transcript has been identified that is generated utilizing a start site in one of the far downstream exons but a protein product associated with this transcript has not been identified. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FPS
Protein Interaction Partner: BCAR1,BCR,CSF2RB,DOK1,DPYSL5,FES,HSH2D,IL4R,IRS1,IRS2,JAK1,JAK2,JAK3,PIK3R1,PLXNA1,RASA1,RASA3,STAT3,BCAR1,BCR,FKBP4,FKBP5,HSH2D,HSP90AA1,HSPA4,PIK3R1,PPID,PSMD13,PTGES3,STAT3
Protein Size: 822 - Molecular Weight
- 93 kDa
- Gene ID
- 2242
- NCBI Accession
- NM_002005, NP_001996
- UniProt
- P07332
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