Fibroblast Growth Factor Receptor Substrate 3 (FRS3) (C-Term) Peptide
FRS3
Reactivity: Human, Mouse
Host: Synthetic
BP, WB
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- Target See all FRS3 products
- FRS3 (Fibroblast Growth Factor Receptor Substrate 3 (FRS3))
- Protein Region
- C-Term
- Origin
- Human, Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- APGPTPHPVR SSDSYAVIDL KKTAAMSDLQ RALPRDDGAV RKTRHNSTDL
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Frs3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- FRS3 (Fibroblast Growth Factor Receptor Substrate 3 (FRS3))
- Synonyms
- MGC82242 Peptide, snt2 Peptide, frs2b Peptide, snt-2 Peptide, frs2beta Peptide, FRS2-beta Peptide, FRS2B Peptide, FRS2beta Peptide, SNT-2 Peptide, SNT2 Peptide, 4930417B13Rik Peptide, AI449674 Peptide, Frs2beta Peptide, Snt2 Peptide, fibroblast growth factor receptor substrate 3 S homeolog Peptide, fibroblast growth factor receptor substrate 3 Peptide, frs3.S Peptide, FRS3 Peptide, frs3 Peptide, Frs3 Peptide
- Background
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Frs3 is an adapter protein that links FGR and NGF receptors to downstream signaling pathways. It is involved in the activation of MAP kinases. Frs3 Down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2.
Alias Symbols: 4930417B13Rik, AI449674, Frs2beta, MGC25496, Snt2
Protein Size: 492 - Molecular Weight
- 54 kDa
- Gene ID
- 107971
- NCBI Accession
- NM_144939, NP_659188
- UniProt
- Q91WJ0
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