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Ferritin, Heavy Polypeptide 1 (FTH1) Peptide

FTH1 Reactivity: Mouse, Human Host: Synthetic WB, BP, IHC
Catalog No. ABIN977123

Quick Overview for Ferritin, Heavy Polypeptide 1 (FTH1) Peptide (ABIN977123)

Target

FTH1 (Ferritin, Heavy Polypeptide 1 (FTH1))

Origin

Mouse, Human

Source

  • 6
  • 4
Synthetic

Application

Western Blotting (WB), Blocking Peptide (BP), Immunohistochemistry (IHC)
  • Characteristics

    This is a synthetic peptide designed for use in combination with anti-FTH1 antibody (Catalog #: ARP54620_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    FTH1 (Ferritin, Heavy Polypeptide 1 (FTH1))

    Background

    FTH1 is the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: FTH, FTHL6, MGC104426, PIG15, PLIF, FHC

    Protein Interaction Partner: CD99,BRD7,CD99,CRMP1,CSF3R,ELL3,FTH1,FTL,FXR2,GOLM1,UBR1,BRD7,CRMP1,ELL3,FTL,FXR2,GOLM1,UBR1

    Protein Size: 183

    Molecular Weight

    21 kDa

    Gene ID

    2495

    NCBI Accession

    NM_002032, NP_002023

    UniProt

    P02794
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