Fat Mass and Obesity-Associated (FTO) (Middle Region) Peptide
FTO
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all FTO products
- FTO (Fat Mass and Obesity-Associated (FTO))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- WWCQPMAQLE ALWKKMEGVT NAVLHEVKRE GLPVEQRNEI LTAILASLTA
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-FTO Antibody(ARP47474_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- FTO (Fat Mass and Obesity-Associated (FTO))
- Synonyms
- AW743446 Peptide, mKIAA1752 Peptide, RGD1305121 Peptide, FTO, alpha-ketoglutarate dependent dioxygenase Peptide, fat mass and obesity associated Peptide, fat mass and obesity associated L homeolog Peptide, FTO Peptide, Fto Peptide, fto.L Peptide
- Background
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The exact function of this gene is not know. Studies in mice suggest that it may be involved in nucleic acid demethylation, and that its mRNA level is regulated by feeding and fasting. Genomewide association studies of type 2 diabetes indicate this gene as a diabetes susceptibility locus. Mutation in this gene has been associated with growth retardation, developmental delay, coarse facies, and early death.
Alias Symbols: KIAA1752, MGC5149
Protein Size: 505 - Molecular Weight
- 58 kDa
- Gene ID
- 79068
- NCBI Accession
- NM_001080432, NP_001073901
- UniProt
- Q9C0B1
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