UDP-Galactose-4-Epimerase (GALE) (Middle Region) Peptide
GALE
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all GALE products
- GALE (UDP-Galactose-4-Epimerase (GALE))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- PQGIPNNLMP YVSQVAIGRR EALNVFGNDY DTEDGTGVRD YIHVVDLAKG
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-GALE Antibody(ARP54394_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- GALE (UDP-Galactose-4-Epimerase (GALE))
- Synonyms
- GALE Peptide, im:7147391 Peptide, wu:fb05f01 Peptide, zgc:136578 Peptide, F15H21.11 Peptide, F15H21_11 Peptide, REB1 Peptide, ROOT EPIDERMAL BULGER1 Peptide, ROOT HAIR DEFECTIVE 1 Peptide, UDP-GLUCOSE 4-EPIMERASE Peptide, UGE4 Peptide, ECK0748 Peptide, galD Peptide, JW0742 Peptide, SMU.888 Peptide, BA5505 Peptide, BA5700 Peptide, VFA0352 Peptide, galE Peptide, 2310002A12Rik Peptide, AI323962 Peptide, 1n569 Peptide, xgale Peptide, SDR1E1 Peptide, UDP-galactose-4-epimerase Peptide, NAD(P)-binding Rossmann-fold superfamily protein Peptide, UDP-galactose 4-epimerase GalE Peptide, UDP-glucose 4-epimerase Peptide, UDP-glucose 4-epimerase GalE Peptide, UDP-glucose/UDP-N-acetylglucosamine 4-epimerase Peptide, galactose-4-epimerase, UDP Peptide, UDP-galactose-4-epimerase L homeolog Peptide, GALE Peptide, gale Peptide, RHD1 Peptide, ECs0787 Peptide, galE Peptide, galE1 Peptide, galE2 Peptide, STY0809 Peptide, galE-2 Peptide, SG0897 Peptide, galD Peptide, Ent638_1250 Peptide, Gale Peptide, gale.L Peptide
- Background
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GALE is an UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardation, with symptoms ranging from mild ('peripheral' form) to severe ('generalized' form).
Alias Symbols: SDR1E1
Protein Interaction Partner: GALE,GALE
Protein Size: 348 - Molecular Weight
- 38 kDa
- Gene ID
- 2582
- NCBI Accession
- NM_001008216, NP_001008217
- UniProt
- Q14376
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