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Gastrin-Releasing Peptide (GRP) (C-Term) Peptide

GRP Reactivity: Human Host: Synthetic WB, BP
Catalog No. ABIN977703
  • Target See all Gastrin-Releasing Peptide (GRP) products
    Gastrin-Releasing Peptide (GRP)
    Protein Region
    C-Term
    Origin
    Human
    Source
    • 4
    Synthetic
    Application
    Western Blotting (WB), Blocking Peptide (BP)
    Sequence
    ENRNHQPPQP KALGNQQPSW DSEDSSNFKD VGSKGKGSQR EGRNPQLNQQ
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-GRP Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    Gastrin-Releasing Peptide (GRP)
    Synonyms
    BLP Peptide, GRP Peptide, BN Peptide, GRP-10 Peptide, preproGRP Peptide, proGRP Peptide, gastrin releasing peptide Peptide, Grp Peptide, GRP Peptide
    Background
    This gene encodes a member of the bombesin-like family of gastrin-releasing peptides. Its preproprotein, following cleavage of a signal peptide, is further processed to produce either the 27 aa gastrin-releasing peptide or the 10 aa neuromedin C. These smaller peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation. These peptides are also likely to play a role in human cancers of the lung, colon, stomach, pancreas, breast, and prostate. Alternative splicing results in multiple transcript variants encoding different isoforms.

    Alias Symbols: BN, GRP-10, preproGRP, proGRP

    Protein Interaction Partner: DPP4,GRPR,MEP1A,MEP1B

    Protein Size: 141
    Molecular Weight
    15 kDa
    Gene ID
    2922
    NCBI Accession
    NM_001012512, NP_001012530
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