Histone Deacetylase 3 (HDAC3) (C-Term) Peptide
HDAC3
Reactivity: Rat
Host: Synthetic
BP, WB
Catalog No. ABIN977905
Quick Overview for Histone Deacetylase 3 (HDAC3) (C-Term) Peptide (ABIN977905)
Target
HDAC3
(Histone Deacetylase 3 (HDAC3))
Origin
Rat
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- DVPADLLTYD RTDEADAEER GPEENYSRPE APNEFYDGDH DNDKESDVEI
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-Hdac3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HDAC3 (Histone Deacetylase 3 (HDAC3))
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Background
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Hdac3 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.Hdac3 is required to repress transcription of the POU1F1 transcription factor. Hdac3 acts as a molecular chaperone for shuttling phosphorylated NR2C1 to PML bodies for sumoylation.
Alias Symbols: Hdac3
Protein Interaction Partner: Hr
Protein Size: 428 -
Molecular Weight
- 49 kDa
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Gene ID
- 84578
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NCBI Accession
- NM_053448, NP_445900
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UniProt
- Q6P6W3
Target
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