Hypoxia Inducible Factor 3, alpha Subunit (HIF3A) Peptide
HIF3A
Reactivity: Human
Host: Synthetic
BP, IHC, WB
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- Target See all HIF3A products
- HIF3A (Hypoxia Inducible Factor 3, alpha Subunit (HIF3A))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-HIF3A antibody (Catalog #: ARP39936_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- HIF3A (Hypoxia Inducible Factor 3, alpha Subunit (HIF3A))
- Synonyms
- HIF-3A Peptide, IPAS Peptide, MOP7 Peptide, PASD7 Peptide, bHLHe17 Peptide, Ipas Peptide, NEPAS Peptide, Mop7 Peptide, HIF3A Peptide, hypoxia inducible factor 3 alpha subunit Peptide, hypoxia inducible factor 3, alpha subunit Peptide, HIF3A Peptide, Hif3a Peptide
- Background
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HIF3A is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression.The protein encoded by this gene is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression. At least three transcript variants encoding three different isoforms have been found for this gene.
Alias Symbols: IPAS, MOP7, PASD7, HIF-3A, bHLHe17
Protein Interaction Partner: EGLN1,EGLN2,EGLN3,HIF1A,VHL
Protein Size: 667 - Molecular Weight
- 72 kDa
- Gene ID
- 64344
- NCBI Accession
- NM_152794, NP_690007
- UniProt
- Q9Y2N7
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