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Ubiquitin-Conjugating Enzyme E2K (UBE2K) Peptide

UBE2K Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN977993

Quick Overview for Ubiquitin-Conjugating Enzyme E2K (UBE2K) Peptide (ABIN977993)

Target

UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))

Origin

Human

Source

  • 9
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Characteristics

    This is a synthetic peptide designed for use in combination with anti-HIP2 antibody (Catalog #: ARP43048_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))

    Background

    HIP2 belongs to the ubiquitin-conjugating enzyme family. It binds selectively to a large region at the N terminus of huntingtin. This interaction is not influenced by the length of the huntingtin polyglutamine tract. This protein has been implicated in the degradation of huntingtin and suppression of apoptosis.The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. It binds selectively to a large region at the N terminus of huntingtin. This interaction is not influenced by the length of the huntingtin polyglutamine tract. This protein has been implicated in the degradation of huntingtin and suppression of apoptosis.

    Alias Symbols: HYPG, LIG, UBE2K, HIP2, UBC1, E2-25K

    Protein Interaction Partner: HTT,HTT,NEDD8,NFKB1,PIAS4,TP53,TRIM3,DDX58,DSTYK,HTT,RNF2,UBE2I

    Protein Size: 200

    Molecular Weight

    22 kDa

    Gene ID

    3093

    NCBI Accession

    NM_005339, NP_005330

    UniProt

    P61086
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