Ubiquitin-Conjugating Enzyme E2K (UBE2K) Peptide
Quick Overview for Ubiquitin-Conjugating Enzyme E2K (UBE2K) Peptide (ABIN977993)
Target
Origin
Source
Application
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-HIP2 antibody (Catalog #: ARP43048_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))
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Background
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HIP2 belongs to the ubiquitin-conjugating enzyme family. It binds selectively to a large region at the N terminus of huntingtin. This interaction is not influenced by the length of the huntingtin polyglutamine tract. This protein has been implicated in the degradation of huntingtin and suppression of apoptosis.The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. It binds selectively to a large region at the N terminus of huntingtin. This interaction is not influenced by the length of the huntingtin polyglutamine tract. This protein has been implicated in the degradation of huntingtin and suppression of apoptosis.
Alias Symbols: HYPG, LIG, UBE2K, HIP2, UBC1, E2-25K
Protein Interaction Partner: HTT,HTT,NEDD8,NFKB1,PIAS4,TP53,TRIM3,DDX58,DSTYK,HTT,RNF2,UBE2I
Protein Size: 200 -
Molecular Weight
- 22 kDa
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Gene ID
- 3093
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NCBI Accession
- NM_005339, NP_005330
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UniProt
- P61086
Target
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