Ubiquitin-Conjugating Enzyme E2K (UBE2K) (N-Term) Peptide
UBE2K
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all UBE2K products
- UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-UBE2K antibody (Catalog #: ARP58011_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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Ubiquitin-Conjugating Enzyme E2K (UBE2K) peptide
UBE2K Reactivity: Human, Cow, Dog, Mouse, Pig Host: Synthetic BP, Imm
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))
- Synonyms
- E2-25K Peptide, HIP2 Peptide, HYPG Peptide, LIG Peptide, UBC1 Peptide, E2-25k Peptide, Hip2 Peptide, Hypg Peptide, Lig Peptide, e2-25k Peptide, hip2 Peptide, hypg Peptide, lig Peptide, AW492011 Peptide, D5Ertd601e Peptide, ube2k Peptide, zgc:103472 Peptide, zgc:110791 Peptide, ubiquitin conjugating enzyme E2 K Peptide, ubiquitin-conjugating enzyme E2K Peptide, ubiquitin conjugating enzyme E2 K S homeolog Peptide, ubiquitin-conjugating enzyme E2Kb (UBC1 homolog, yeast) Peptide, ubiquitin-conjugating enzyme E2Ka (UBC1 homolog, yeast) Peptide, UBE2K Peptide, Ube2k Peptide, ube2k.S Peptide, ube2k Peptide, ube2kb Peptide, ube2ka Peptide
- Background
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UBE2K belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation.The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene.
Alias Symbols: DKFZp564C1216, DKFZp686J24237, E2-25K, HIP2, HYPG, LIG, UBC1
Protein Interaction Partner: HTT,HTT,NEDD8,NFKB1,PIAS4,TP53,TRIM3,DDX58,DSTYK,HTT,RNF2,UBE2I
Protein Size: 200 - Molecular Weight
- 22 kDa
- Gene ID
- 3093
- NCBI Accession
- NM_005339, NP_005330
- UniProt
- P61086
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