Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) (HNRNPU) (C-Term) Peptide
HNRNPU
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all HNRNPU products
- HNRNPU (Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) (HNRNPU))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- EITYVELQKE EAQKLLEQYK EESKKALPPE KKQNTGSKKS NKNKSGKNQF
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-HNRNPU Antibody(ARP40518_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- HNRNPU (Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) (HNRNPU))
- Synonyms
- AA408410 Peptide, AI256620 Peptide, AL024194 Peptide, AL024437 Peptide, AW557595 Peptide, C86794 Peptide, Hnrpu Peptide, SAFA Peptide, Sp120 Peptide, hnRNP U Peptide, SN1 Peptide, HNRPU Peptide, SAF-A Peptide, U21.1 Peptide, saf-a Peptide, heterogeneous nuclear ribonucleoprotein U Peptide, heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) S homeolog Peptide, heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) Peptide, Hnrnpu Peptide, HNRNPU Peptide, hnrnpu.S Peptide
- Background
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HNRNPU belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. HNRNPU contains a RNA binding domain and scaffold-associated region (SAR)-specific bipartite DNA-binding domain. This protein is also thought to be involved in the packaging of hnRNA into large ribonucleoprotein complexes. During apoptosis, this protein is cleaved in a caspase-dependent way. But this cleavage does not affect the function of the encoded protein in RNA metabolism.
Alias Symbols: HNRPU, SAF-A, U21.1, hnRNP U
Protein Interaction Partner: ACTB,CR2,ACTB,BTRC,CASP3,CD5,CR2,ELL,EP300,GRIN1,GRIN2D,GTF2H1,NDN,NDRG1,NR3C1,POU3F4,PRMT1,PTPN11,SMN2,SREK1,STAU1,SYK,YAP1,ZNF689,CDK7,CDK9,EP300,GPN1,GTF2F1,HNRNPH1,MAX,MYC,NDN,NR3C1,POLR2A,POLR2J,POU3F4,PRMT1,RUVBL2,SFN
Protein Size: 825 - Molecular Weight
- 90 kDa
- Gene ID
- 3192
- NCBI Accession
- NM_031844, NP_114032
- UniProt
- Q00839
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