Heterogeneous Nuclear Ribonucleoprotein D (HNRNPD) Peptide
HNRNPD
Reactivity: Human
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN978106
$160.46
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100 μg
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Quick Overview for Heterogeneous Nuclear Ribonucleoprotein D (HNRNPD) Peptide (ABIN978106)
Target
HNRNPD/AUF1 (HNRNPD)
(Heterogeneous Nuclear Ribonucleoprotein D (HNRNPD))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-HNRPD antibody (Catalog #: ARP40239_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HNRNPD/AUF1 (HNRNPD) (Heterogeneous Nuclear Ribonucleoprotein D (HNRNPD))
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Background
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HNRPD belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein has two repeats of quasi-RRM domains that bind to RNAs. It localizes to both the nucleus and the cytoplasm. This protein is implicated in the regulation of mRNA stability. This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It localizes to both the nucleus and the cytoplasm. This protein is implicated in the regulation of mRNA stability. Alternative splicing of this gene results in four transcript variants.
Alias Symbols: P37, AUF1, AUF1A, HNRPD, hnRNPD0
Protein Interaction Partner: SAFB,SAFB,CSDE1,EXOSC4,GSK3B,HNRNPD,IGF2BP2,LDHA,LSM5,PABPC1,PCBP1,PCBP2,PCSK7,PRKACA,SAFB,SFN,SFRS12,SUMO4,SYNCRIP,TNPO1,UBE2I,YBX1,CDK9,EIF4G1,GPN1,HNRNPD,HNRNPH1,HSPA4,HSPA8,HSPB1,KHDRBS2,LSM5,MEPCE,SAFB,TRNAN1
Protein Size: 355 -
Molecular Weight
- 39 kDa
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Gene ID
- 3184
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NCBI Accession
- NM_031370, NP_112738
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UniProt
- Q14103
Target
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