Heterogeneous Nuclear Ribonucleoprotein H1 (H) (HNRNPH1) (Middle Region) Peptide
Quick Overview for Heterogeneous Nuclear Ribonucleoprotein H1 (H) (HNRNPH1) (Middle Region) Peptide (ABIN978110)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-HNRPH1 antibody (Catalog #: ARP58479_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HNRNPH1 (Heterogeneous Nuclear Ribonucleoprotein H1 (H) (HNRNPH1))
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Background
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HNRPH1 belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. This protein has three repeats of quasi-RRM domains that bind to RNAs. It is very similar to the family member HNRPF. This gene is thought to be potentially involved in hereditary lymphedema type I phenotype.This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. It is very similar to the family member HNRPF. This gene is thought to be potentially involved in hereditary lymphedema type I phenotype. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DKFZp686A15170, HNRPH, hnRNPH, HNRPH1
Protein Interaction Partner: CRMP1,HNRNPF,NCBP1,NCBP2,NDRG1,SFRS12,SUMO4,TCERG1,TOM1L1,YWHAG,CCT4,CCT5,CDK9,CPNE1,CRMP1,DDX17,DDX5,GPN1,HNRNPA1,HNRNPA2B1,HNRNPD,HNRNPF,HNRNPH2,HNRNPK,HNRNPM,HNRNPU,HSPD1,KHDRBS2,KHSRP,KPNA2,MEPCE,NCBP1,NCBP2,RQCD1,SYNCRIP,TCERG1,YKT6,YTHDF2
Protein Size: 449 -
Molecular Weight
- 49 kDa
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Gene ID
- 3187
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NCBI Accession
- NM_005520, NP_005511
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UniProt
- P31943
Target
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