Histamine Receptor H1 (HRH1) (Middle Region) Peptide
HRH1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all HRH1 products
- HRH1 (Histamine Receptor H1 (HRH1))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- ENPKGDAKKP GKESPWEVLK RKPKDAGGGS VLKSPSQTPK EMKSPVVFSQ
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-HRH1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- HRH1 (Histamine Receptor H1 (HRH1))
- Synonyms
- H1-R Peptide, hisH1 Peptide, Bphs Peptide, H1R Peptide, HH1R Peptide, Hir Peptide, HRH1 Peptide, H1 Peptide, Hisr Peptide, histamine receptor H1 Peptide, histamine receptor H 1 Peptide, HRH1 Peptide, Hrh1 Peptide, hrh1 Peptide
- Background
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Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene was thought to be intronless until recently. The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Alias Symbols: H1-R, hisH1
Protein Size: 487 - Molecular Weight
- 56 kDa
- Gene ID
- 3269
- NCBI Accession
- NM_000861, NP_000852
- UniProt
- P35367
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