Heat Shock 22kDa Protein 8 (HSPB8) (Middle Region) Peptide
HSPB8
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all HSPB8 products
- HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- PEELMVKTKD GYVEVSGKHE EKQQEGGIVS KNFTKKIQLP AEVDPVTVFA
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-HSPB8 Antibody(ARP55036_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))
- Synonyms
- CMT2L Peptide, DHMN2 Peptide, E2IG1 Peptide, H11 Peptide, HMN2 Peptide, HMN2A Peptide, HSP22 Peptide, MGC64408 Peptide, hsc70 Peptide, wu:fb01g06 Peptide, wu:fi48b06 Peptide, fc09c11 Peptide, wu:fc04b04 Peptide, wu:fc09c11 Peptide, zgc:64202 Peptide, AU018630 Peptide, AW413033 Peptide, Cryac Peptide, D5Ucla4 Peptide, H11K Peptide, HSP20-like Peptide, Hsp22 Peptide, heat shock protein family B (small) member 8 Peptide, heat shock protein family B (small) member 8 L homeolog Peptide, heat shock protein 8 Peptide, heat shock protein b8 Peptide, HSPB8 Peptide, hspb8.L Peptide, hspa8 Peptide, hspb8 Peptide, Hspb8 Peptide
- Background
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HSPB8 belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of HSPB8 protein is induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, HSPB8 appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in the encoding HSPB8 gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.
Alias Symbols: CMT2L, DHMN2, E2IG1, H11, HMN2, HMN2A, HSP22
Protein Interaction Partner: HSPB1,HSPB8,BAG3,CSNK2A1,HSPB1,HSPB6,HSPB7,HSPB8,MAPK3,PRKCA,BAG3,HSPB1,HSPB2,HSPB7,HSPB8
Protein Size: 196 - Molecular Weight
- 21 kDa
- Gene ID
- 26353
- NCBI Accession
- NM_014365, NP_055180
- UniProt
- Q9UJY1
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