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HUS1 Checkpoint Homolog B (HUS1B) Peptide

HUS1B Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN978361
  • Target See all HUS1B products
    HUS1B (HUS1 Checkpoint Homolog B (HUS1B))
    Origin
    Human
    Source
    • 1
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-HUS1B antibody (Catalog #: ARP52871_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    HUS1B (HUS1 Checkpoint Homolog B (HUS1B))
    Synonyms
    HUS1B Peptide, RP11-532F6.1 Peptide, HUS1 checkpoint clamp component B Peptide, HUS1B Peptide, Hus1b Peptide
    Background
    HUS1Bis most closely related to HUS1, a component of a cell cycle checkpoint protein complex involved in cell cycle arrest in response to DNA damage. HUS1B can interact with the check point protein RAD1 but not with RAD9. Overexpression of HUS1B has been shown to induce cell death, which suggests a related but distinct role of this protein, as compared to the HUS1.The protein encoded by this gene is most closely related to HUS1, a component of a cell cycle checkpoint protein complex involved in cell cycle arrest in response to DNA damage. This protein can interact with the check point protein RAD1 but not with RAD9. Overexpression of this protein has been shown to induce cell death, which suggests a related but distinct role of this protein, as compared to the HUS1.

    Alias Symbols: MGC126746, MGC126748, RP11-532F6.1

    Protein Interaction Partner: HUS1,RAD1,RAD9A,RAD9B,RAD1,RAD9A,RAD9B

    Protein Size: 278
    Molecular Weight
    31 kDa
    Gene ID
    135458
    NCBI Accession
    NM_148959, NP_683762
    UniProt
    Q8NHY5
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