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Hyaluronidase-1 (HYAL1) (N-Term) Peptide

HYAL1 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN978363
  • Target See all HYAL1 products
    HYAL1 (Hyaluronidase-1 (HYAL1))
    Protein Region
    N-Term
    Origin
    Human
    Source
    • 5
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-HYAL1 antibody (Catalog #: ARP50813_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    HYAL1 (Hyaluronidase-1 (HYAL1))
    Synonyms
    HYAL-1 Peptide, LUCA1 Peptide, NAT6 Peptide, Hya1 Peptide, Hyal-1 Peptide, hyaluronoglucosaminidase 1 Peptide, HYAL1 Peptide, Hyal1 Peptide
    Background
    HYAL1 is a lysosomal hyaluronidase. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. This enzyme is active at an acidic pH and is the major hyaluronidase in plasma. Mutations in this gene are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency. This gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. Multiple transcript variants encoding different isoforms have been found for this gene.This gene encodes a lysosomal hyaluronidase. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. This enzyme is active at an acidic pH and is the major hyaluronidase in plasma. Mutations in this gene are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. Multiple transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: HYAL-1, LUCA1, MGC45987, NAT6

    Protein Size: 435
    Molecular Weight
    45 kDa
    Gene ID
    3373
    NCBI Accession
    NM_153282, NP_695014
    UniProt
    Q12794
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