Integrin Alpha2b (CD41) (N-Term) Peptide
CD41
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN978653
$160.46
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100 μg
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Quick Overview for Integrin Alpha2b (CD41) (N-Term) Peptide (ABIN978653)
Target
Integrin Alpha2b (CD41)
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- QGLGASVVSW SDVIVACAPW QHWNVLEKTE EAEKTPVGSC FLAQPESGRR
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-ITGA2B Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Integrin Alpha2b (CD41)
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Background
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ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.
Alias Symbols: CD41, CD41B, GP2B, GPIIb, GTA, HPA3, GT, BDPLT2
Protein Interaction Partner: ITGB3,AUP1,CALR,CD36,CIB1,CLNS1A,COL1A2,COL2A1,F2,FGA,GRB2,ITGA2B,ITGB3,TLN1,VWF,AUP1,CD36,CLNS1A,COL2A1,F2,GRB2,RNF181
Protein Size: 1039 -
Molecular Weight
- 16 kDa
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Gene ID
- 3674
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NCBI Accession
- NM_000419, NP_000410
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UniProt
- P08514
Target
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