Kinesin Associated Protein 3 (KIFAP3) (Middle Region) Peptide
KIFAP3
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN978973
$160.46
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100 μg
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Quick Overview for Kinesin Associated Protein 3 (KIFAP3) (Middle Region) Peptide (ABIN978973)
Target
KIFAP3
(Kinesin Associated Protein 3 (KIFAP3))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- WLEMVESRQM DESEQYLYGD DRIEPYIHEG DILERPDLFY NSDGLIASEG
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-KIFAP3 Antibody(ARP55128_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- KIFAP3 (Kinesin Associated Protein 3 (KIFAP3))
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Background
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The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras, one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by this gene contains 9 'Armadillo' repeats and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein.
Alias Symbols: FLJ22818, KAP3, SMAP, Smg-GDS, dJ190I16.1, KAP-3
Protein Interaction Partner: APC,KIF3B,KIFAP3,MAP3K10,MINK1,RAP1GDS1,RBFOX1,RPGR,SMC3,SRC,APC,AR,MAP3K10,MAP3K11,RAP1GDS1,SMC3,SRC
Protein Size: 792 -
Molecular Weight
- 91 kDa
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Gene ID
- 22920
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NCBI Accession
- NM_014970, NP_055785
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UniProt
- Q92845
Target
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