Kin of IRRE Like 1 (NEPH1) (Middle Region) Peptide
NEPH1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all KIRREL (NEPH1) products
- KIRREL (NEPH1) (Kin of IRRE Like 1 (NEPH1))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-KIRREL antibody (Catalog #: ARP47408_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- KIRREL (NEPH1) (Kin of IRRE Like 1 (NEPH1))
- Synonyms
- NEPH1 Peptide, 6720469N11Rik Peptide, Kirrel1 Peptide, Neph1 Peptide, nephrin related Peptide, kirre like nephrin family adhesion molecule 1 Peptide, kin of IRRE like (Drosophila) Peptide, Smp_104390 Peptide, Smp_140170 Peptide, KIRREL1 Peptide, Kirrel Peptide, Kirrel1 Peptide
- Background
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KIRREL (NEPH1) is a member of the nephrin-like protein family, which includes NEPH2 and NEPH3. The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2), and the genes are expressed in kidney podocytes, cells involved in ensuring size- and charge-selective ultrafiltration. NEPH1 is a member of the nephrin-like protein family, which includes NEPH2 (MIM 607761) and NEPH3 (MIM 607762). The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2, MIM 604766), and the genes are expressed in kidney podocytes, cells involved in ensuring size- and charge-selective ultrafiltration (Sellin et al., 2003 [PubMed 12424224]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-337 AY302131.1 1-337 338-3211 BC109193.1 1-2874 3212-3609 AK001707.1 1904-2301 3610-3628 BC082969.1 2273-2291
Alias Symbols: FLJ10845, MGC129542, MGC129543, NEPH1
Protein Interaction Partner: KIRREL,NPHS1,NPHS2,TJP1,KIRREL,NPHS1,TJP1
Protein Size: 593 - Molecular Weight
- 66 kDa
- Gene ID
- 55243
- NCBI Accession
- NM_018240, NP_060710
- UniProt
- Q96J84
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