Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase) (KMO) (N-Term) Peptide
Quick Overview for Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase) (KMO) (N-Term) Peptide (ABIN979094)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Sequence
- VIGGGLVGSL QACFLAKRNF QIDVYEARED TRVATFTRGR SINLALSHRG
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-KMO Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- KMO (Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase) (KMO))
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Background
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This gene encodes a mitochondrion outer membrane protein that catalyzes the hydroxylation of L-tryptophan metabolite, L-kynurenine, to form L-3-hydroxykynurenine. Studies in yeast identified this gene as a therapeutic target for Huntington disease.
Alias Symbols: dJ317G22.1
Protein Size: 486 -
Molecular Weight
- 56 kDa
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Gene ID
- 8564
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NCBI Accession
- NM_003679, NP_003670
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UniProt
- O15229
Target
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