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Keratin 1 (KRT1) (Middle Region) Peptide

KRT1 Reactivity: Human Host: Synthetic BP, IHC, WB
Catalog No. ABIN979113
  • Target See all Cytokeratin 1 (KRT1) products
    Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 1
    Synthetic
    Application
    Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-KRT1 antibody (Catalog #: ARP42278_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))
    Synonyms
    CK1 Peptide, EHK Peptide, EHK1 Peptide, EPPK Peptide, K1 Peptide, KRT1A Peptide, NEPPK Peptide, Krt-2.1 Peptide, Krt2-1 Peptide, Krt86 Peptide, KRT1 Peptide, Kb1 Peptide, KER1 Peptide, CK-1 Peptide, Keratin-1 Peptide, keratin 1 Peptide, KRT1 Peptide, Krt1 Peptide
    Background
    KRT1 is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma.The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: CK1, EHK1, K1, KRT1A, EHK, EPPK, NEPPK

    Protein Interaction Partner: CALB2,DSP,EVPL,F12,KNG1,KRT5,MBL2,PRKCE,YWHAQ,CSTA,DSP,FANCA,FANCC,IVL,KNG1,LOR,MBL2,PI3,PRKCE

    Protein Size: 644
    Molecular Weight
    66 kDa
    Gene ID
    3848
    NCBI Accession
    NM_006121, NP_006112
    UniProt
    P04264
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