Ligase I, DNA, ATP-Dependent (LIG1) (Middle Region) Peptide
LIG1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all LIG1 products
- LIG1 (Ligase I, DNA, ATP-Dependent (LIG1))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- PSVTSFILDT EAVAWDREKK QIQPFQVLTT RKRKEVDASE IQVQVCLYAF
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-LIG1 Antibody(ARP54308_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- LIG1 (Ligase I, DNA, ATP-Dependent (LIG1))
- Synonyms
- ATLIG1 Peptide, DNA ligase 1 Peptide, T6D22.23 Peptide, ligI Peptide, AL033288 Peptide, LigI Peptide, lig1 Peptide, wu:fc54a11 Peptide, DNA ligase 1 Peptide, DNA ligase 1, putative Peptide, ligase I, DNA, ATP-dependent L homeolog Peptide, ligase I, DNA, ATP-dependent Peptide, LIG1 Peptide, PB000674.02.0 Peptide, PTRG_06243 Peptide, PKH_140260 Peptide, lig1.L Peptide, Lig1 Peptide, lig-1 Peptide, lig1 Peptide
- Background
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LIG1is DNA ligase I, with functions in DNA replication and the base excision repair process. Mutations in LIG1 that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents.
Alias Symbols: MGC117397, MGC130025
Protein Interaction Partner: PCNA,CSNK2A1,INPP1,MRE11A,PCNA,TUBB3,MRE11A,PCNA,UBC
Protein Size: 919 - Molecular Weight
- 102 kDa
- Gene ID
- 3978
- NCBI Accession
- NM_000234, NP_000225
- UniProt
- P18858
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