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Mediterranean Fever (MEFV) (N-Term) Peptide

MEFV Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN979971
  • Target See all MEFV products
    MEFV (Mediterranean Fever (MEFV))
    Protein Region
    N-Term
    Origin
    Human
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-MEFV antibody (Catalog #: ARP37973_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    MEFV (Mediterranean Fever (MEFV))
    Background
    MEFV was identified as the gene that when mutated causes Mediterranean fever, a hereditary periodic fever syndrome. MEFV is expressed in granulocytes and myeloid bone marrow precursors. This gene encodes a protein, also known as pyrin or marenostrin, that is an important modulator of innate immunity. Mutations in this gene are associated with Mediterranean fever, a hereditary periodic fever syndrome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: FMF, MEF, MGC126560, MGC126586, TRIM20

    Protein Interaction Partner: COG5,PSTPIP1,PYCARD,COG5,PYCARD

    Protein Size: 781
    Molecular Weight
    86 kDa
    Gene ID
    4210
    NCBI Accession
    NM_000243, NP_000234
    UniProt
    O15553
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