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Mediator of Cell Motility 1 (MEMO1) (Middle Region) Peptide

MEMO1 Reactivity: Human, Mouse Host: Synthetic BP, WB
Catalog No. ABIN979984
  • Target See all MEMO1 products
    MEMO1 (Mediator of Cell Motility 1 (MEMO1))
    Protein Region
    Middle Region
    Origin
    Human, Mouse
    Source
    • 4
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    CHWGQRFRYS YYDESQGEIY RSIEHLDKMG MSIIEQLDPV SFSNYLKKYH
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-Memo1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    MEMO1 (Mediator of Cell Motility 1 (MEMO1))
    Synonyms
    MGC89105 Peptide, C2orf4 Peptide, MEMO Peptide, NS5ATP7 Peptide, 0610016J10Rik Peptide, D930048L02Rik Peptide, RGD1309929 Peptide, fi04d12 Peptide, wu:fi04d12 Peptide, zgc:55290 Peptide, mediator of cell motility 1 Peptide, mediator of cell motility 1 L homeolog Peptide, MEMO1 Peptide, memo1 Peptide, Memo1 Peptide, memo1.L Peptide
    Background
    Memo1 may control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. It is a mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization.

    Alias Symbols: 0610016J10Rik, D930048L02Rik

    Protein Size: 297
    Molecular Weight
    34 kDa
    Gene ID
    76890
    NCBI Accession
    NM_133771, NP_598532
    UniProt
    Q91VH6
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