Mortality Factor 4 Like 1 (MORF4L1) (Middle Region) Peptide
MORF4L1
Reactivity: Mouse
Host: Synthetic
BP, WB
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- Target See all MORF4L1 products
- MORF4L1 (Mortality Factor 4 Like 1 (MORF4L1))
- Protein Region
- Middle Region
- Origin
- Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- LQQKNVEVKT KKNKQKTPGN GDGGSTSETP QPPRKKRARV DPTVENEETF
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Morf4l1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MORF4L1 (Mortality Factor 4 Like 1 (MORF4L1))
- Synonyms
- Eaf3 Peptide, HsT17725 Peptide, MEAF3 Peptide, MORFRG15 Peptide, MRG15 Peptide, S863-6 Peptide, TEG-189 Peptide, Tex189 Peptide, mKIAA4002 Peptide, MORF4L2 Peptide, CG6363 Peptide, DmMRG15 Peptide, Dmel\\CG6363 Peptide, Dmrg15 Peptide, Mrg15 Peptide, dMRG15 Peptide, dMrg15 Peptide, l(3)j6A3 Peptide, zgc:92289 Peptide, mortality factor 4 like 1 Peptide, MORF-related gene 15 Peptide, MRG15 Peptide, mortality factor 4 like 1 S homeolog Peptide, MORF4L1 Peptide, Morf4l1 Peptide, MRG15 Peptide, CpipJ_CPIJ013367 Peptide, morf4l1.S Peptide, morf4l1 Peptide
- Background
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Morf4l1 is a component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage.
Alias Symbols: KIAA4002, MGC102415, MGC103105, MGC118047, MORFRG15, MRG15, TEG-189, Tex189, mKIAA4002
Protein Interaction Partner: PFN2,SIN3A,TLE1
Protein Size: 362 - Molecular Weight
- 41 kDa
- Gene ID
- 21761
- NCBI Accession
- NM_001039147, NP_001034236
- UniProt
- P60762
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