MUS81 Endonuclease Homolog (MUS81) (C-Term) Peptide
MUS81
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN980382
$160.46
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100 μg
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United States
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Quick Overview for MUS81 Endonuclease Homolog (MUS81) (C-Term) Peptide (ABIN980382)
Target
MUS81
(MUS81 Endonuclease Homolog (MUS81))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- GETRGGGHRP ELLRELQRLH VTHTVRKLHV GDFVWVAQET NPRDPANPGE
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-MUS81 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MUS81 (MUS81 Endonuclease Homolog (MUS81))
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Background
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MUS81 interacts with EME1 and EME2 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. It may be required in mitosis for the processing of stalled or collapsed replication forks.
Alias Symbols: FLJ21012, FLJ44872, SLX3
Protein Interaction Partner: CHEK2,EME1,MUS81,CHEK2,EME1,SLX1B,SLX4,SUMO2,TERF2,TERT
Protein Size: 551 -
Molecular Weight
- 61 kDa
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Gene ID
- 80198
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NCBI Accession
- NM_025128, NP_079404
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UniProt
- Q96NY9
Target
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