Neural Precursor Cell Expressed, Developmentally Down-Regulated 9 (NEDD9) Peptide
NEDD9
Reactivity: Human
Host: Synthetic
BP, WB, IHC
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- Target See all NEDD9 products
- NEDD9 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 9 (NEDD9))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-NEDD9 antibody (Catalog #: ARP51210_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- NEDD9 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 9 (NEDD9))
- Synonyms
- NEDD9 Peptide, CAS-L Peptide, CAS2 Peptide, CASL Peptide, CASS2 Peptide, HEF1 Peptide, Cas-L Peptide, CasL Peptide, E230025G09Rik Peptide, neural precursor cell expressed, developmentally down-regulated 9 Peptide, neural precursor cell expressed, developmentally down-regulated gene 9 Peptide, NEDD9 Peptide, Nedd9 Peptide
- Background
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Variation in NEDD9 is associated wih susceptibility to late-onset Alzheimer and Parkinson diseases. Changes in expression of the scaffold protein HEF1/CAS-L/NEDD9 were found to be a potent prometastatic stimulus in melanoma and other cancers.
Alias Symbols: CAS-L, CASL, HEF1, dJ49G10.2, dJ761I2.1, CAS2, CASS2
Protein Interaction Partner: FZR1,SMAD3,ABL1,BCAR1,BCAR3,CDH1,CHAT,CRK,CRKL,DIMT1L,ELSPBP1,FYN,ID2,ITCH,LCK,LYN,MICAL1,NCK1,NEDD9,PTK2,PTK2B,PTPN11,PTPN12,PXN,RAPGEF1,SH2D3C,SMAD1,SMAD2,SMAD3,TCF3,TRIP6,ZYX,ABL1,BCAR1,BCAR3,CDH1,CRK,CRKL,ELSPBP1,FYN,ID2,ITCH,LCK,LYN,MICAL1,NCK1,NEDD9,PTK2,PTK2B,PTPN12,PXN,RAPGEF1,SH2D3C,SMAD1,SMAD2,SMAD3,TRIP6,ZYX
Protein Size: 834 - Molecular Weight
- 93 kDa
- Gene ID
- 4739
- NCBI Accession
- NM_006403, NP_006394
- UniProt
- Q14511
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