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Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) Peptide

NFE2L2 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN980656
  • Target See all NRF2 (NFE2L2) products
    NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))
    Origin
    Human
    Source
    • 6
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-NFE2L2 antibody (Catalog #: ARP38745_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))
    Synonyms
    Nrf2 Peptide, nfe2l2 Peptide, wu:fc15g09 Peptide, wu:fj67e03 Peptide, NF-E2R2 Peptide, NRF2 Peptide, AI194320 Peptide, nuclear factor, erythroid 2-like 2a Peptide, nuclear factor, erythroid 2 like 2 S homeolog Peptide, nuclear factor, erythroid 2 like 2 Peptide, nuclear factor, erythroid derived 2, like 2 Peptide, nuclear factor, erythroid 2-like 2 Peptide, nfe2l2a Peptide, nfe2l2.S Peptide, NFE2L2 Peptide, Nfe2l2 Peptide
    Background
    NFE2 (MIM 601490), NFE2L1 (MIM 163260), and NFE2L2 comprise a family of human genes encoding basic leucine zipper (bZIP) transcription factors. They share highly conserved regions that are distinct from other bZIP families, such as JUN (MIM 165160) and FOS (MIM 164810), although remaining regions have diverged considerably from each other. NFE2L2 may be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.NFE2 (MIM 601490), NFE2L1 (MIM 163260), and NFE2L2 comprise a family of human genes encoding basic leucine zipper (bZIP) transcription factors. They share highly conserved regions that are distinct from other bZIP families, such as JUN (MIM 165160) and FOS (MIM 164810), although remaining regions have diverged considerably from each other (Chan et al., 1995).[supplied by OMIM].

    Alias Symbols: NRF2

    Protein Interaction Partner: ATF4,CASP1,CASP3,CHD6,COPS7A,CREBBP,EIF2AK3,JUN,JUND,KEAP1,MAFF,MAFG,MAFK,NFE2,PMF1,PPARG,PRKCD,CREBBP,EIF2AK3,JUN,KEAP1,Keap1,MAFF,MAFK,PMF1,PPARG,UBC

    Protein Size: 605
    Molecular Weight
    68 kDa
    Gene ID
    4780
    NCBI Accession
    NM_006164, NP_006155
    UniProt
    Q16236
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