Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) Peptide
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- Target See all NRF2 (NFE2L2) products
- NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-NFE2L2 antibody (Catalog #: ARP38745_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))
- Synonyms
- Nrf2 Peptide, nfe2l2 Peptide, wu:fc15g09 Peptide, wu:fj67e03 Peptide, NF-E2R2 Peptide, NRF2 Peptide, AI194320 Peptide, nuclear factor, erythroid 2-like 2a Peptide, nuclear factor, erythroid 2 like 2 S homeolog Peptide, nuclear factor, erythroid 2 like 2 Peptide, nuclear factor, erythroid derived 2, like 2 Peptide, nuclear factor, erythroid 2-like 2 Peptide, nfe2l2a Peptide, nfe2l2.S Peptide, NFE2L2 Peptide, Nfe2l2 Peptide
- Background
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NFE2 (MIM 601490), NFE2L1 (MIM 163260), and NFE2L2 comprise a family of human genes encoding basic leucine zipper (bZIP) transcription factors. They share highly conserved regions that are distinct from other bZIP families, such as JUN (MIM 165160) and FOS (MIM 164810), although remaining regions have diverged considerably from each other. NFE2L2 may be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.NFE2 (MIM 601490), NFE2L1 (MIM 163260), and NFE2L2 comprise a family of human genes encoding basic leucine zipper (bZIP) transcription factors. They share highly conserved regions that are distinct from other bZIP families, such as JUN (MIM 165160) and FOS (MIM 164810), although remaining regions have diverged considerably from each other (Chan et al., 1995).[supplied by OMIM].
Alias Symbols: NRF2
Protein Interaction Partner: ATF4,CASP1,CASP3,CHD6,COPS7A,CREBBP,EIF2AK3,JUN,JUND,KEAP1,MAFF,MAFG,MAFK,NFE2,PMF1,PPARG,PRKCD,CREBBP,EIF2AK3,JUN,KEAP1,Keap1,MAFF,MAFK,PMF1,PPARG,UBC
Protein Size: 605 - Molecular Weight
- 68 kDa
- Gene ID
- 4780
- NCBI Accession
- NM_006164, NP_006155
- UniProt
- Q16236
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