Nuclear Factor, Interleukin 3 Regulated (NFIL3) Peptide
NFIL3
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all NFIL3 products
- NFIL3 (Nuclear Factor, Interleukin 3 Regulated (NFIL3))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-NFIL3 antibody (Catalog #: ARP31177_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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Nuclear Factor, Interleukin 3 Regulated (NFIL3) peptide
NFIL3 Reactivity: Human, Mouse, Rat Host: Synthetic BP, Imm
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- NFIL3 (Nuclear Factor, Interleukin 3 Regulated (NFIL3))
- Synonyms
- e4bp4 Peptide, il3bp1 Peptide, nfil3a Peptide, nf-il3a Peptide, MGC107826 Peptide, NFIL3 Peptide, E4BP4 Peptide, IL3BP1 Peptide, NF-IL3A Peptide, NFIL3A Peptide, E4BP4-1 Peptide, zgc:100867 Peptide, AV225605 Peptide, nuclear factor, interleukin 3 regulated Peptide, nuclear factor, interleukin 3 regulated L homeolog Peptide, nuclear factor, interleukin 3, regulated Peptide, nfil3 Peptide, NFIL3 Peptide, Nfil3 Peptide, nfil3.L Peptide
- Background
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NFIL3 is a basic leucine zipper (bZIP) transcription factor that represses or activates transcription in non-osteoblastic cells. NFIL3 play a role in attenuation of PTH target gene transcription in osteoblasts. NFIL3 repression domain interacts specifically with the TBP binding repressor protein Dr1.Glucocorticoid-mediated upregulation of the bZIP transcriptional repressor gene, NFIL3, is dependent on [Ca2+]i levels, and correlates with Glucocorticoid-evoked apoptosis of Glucocorticoid-sensitive CEM-C7-14 cells. NFIL3 is involved in a distinct growth factor-regulated signaling pathway that is responsible for the survival of early B-cell progenitors, and whose alteration by E2A-HLF leads to childhood B lineage leukemia.
Alias Symbols: E4BP4, IL3BP1, NF-IL3A, NFIL3A
Protein Interaction Partner: CREB3,DR1,NFIL3,DR1
Protein Size: 462 - Molecular Weight
- 51 kDa
- Gene ID
- 4783
- NCBI Accession
- NM_005384, NP_005375
- UniProt
- Q16649
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