Nitric Oxide Synthase 1 (Neuronal) Adaptor Protein (NOS1AP) (C-Term) Peptide
NOS1AP
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN980803
$160.46
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100 μg
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Quick Overview for Nitric Oxide Synthase 1 (Neuronal) Adaptor Protein (NOS1AP) (C-Term) Peptide (ABIN980803)
Target
NOS1AP
(Nitric Oxide Synthase 1 (Neuronal) Adaptor Protein (NOS1AP))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- PEDTPPPAQG EALLGGLELI KFRESGIASE YESNTDESEE RDSWSQEELP
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-NOS1AP Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- NOS1AP (Nitric Oxide Synthase 1 (Neuronal) Adaptor Protein (NOS1AP))
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Background
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This gene encodes a cytosolic protein that binds to the signaling molecule, neuronal nitric oxide synthase (nNOS). This protein has a C-terminal PDZ-binding domain that mediates interactions with nNOS and an N-terminal phosphotyrosine binding (PTB) domain that binds to the small monomeric G protein, Dexras1. Studies of the related mouse and rat proteins have shown that this protein functions as an adapter protein linking nNOS to specific targets, such as Dexras1 and the synapsins. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: 6330408P19Rik, CAPON
Protein Interaction Partner: LRP1,LRP2,NOS1,RASD1,SYN1,SYN2,SYN3,LRP1,LRP2,LRP8,NOS1,RASD1,SYN1,SYN2,SYN3
Protein Size: 586 -
Molecular Weight
- 63 kDa
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Gene ID
- 9722
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NCBI Accession
- NM_001126060
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UniProt
- O75052
Target
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