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Nitric Oxide Synthase 1 (Neuronal) Adaptor Protein (NOS1AP) (C-Term) Peptide

NOS1AP Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN980803
  • Target See all NOS1AP products
    NOS1AP (Nitric Oxide Synthase 1 (Neuronal) Adaptor Protein (NOS1AP))
    Protein Region
    C-Term
    Origin
    Human
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    PEDTPPPAQG EALLGGLELI KFRESGIASE YESNTDESEE RDSWSQEELP
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-NOS1AP Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    NOS1AP (Nitric Oxide Synthase 1 (Neuronal) Adaptor Protein (NOS1AP))
    Synonyms
    MGC78853 Peptide, Capon Peptide, MGC145362 Peptide, 6330408P19Rik Peptide, CAPON Peptide, nitric oxide synthase 1 adaptor protein Peptide, nitric oxide synthase 1 adaptor protein L homeolog Peptide, nitric oxide synthase 1 (neuronal) adaptor protein a Peptide, carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein Peptide, chromosome 18 C1orf226 homolog Peptide, nitric oxide synthase 1 (neuronal) adaptor protein Peptide, NOS1AP Peptide, nos1ap.L Peptide, nos1apa Peptide, LOC609484 Peptide, nos1ap Peptide, LOC100058633 Peptide, C18H1orf226 Peptide, Nos1ap Peptide
    Background
    This gene encodes a cytosolic protein that binds to the signaling molecule, neuronal nitric oxide synthase (nNOS). This protein has a C-terminal PDZ-binding domain that mediates interactions with nNOS and an N-terminal phosphotyrosine binding (PTB) domain that binds to the small monomeric G protein, Dexras1. Studies of the related mouse and rat proteins have shown that this protein functions as an adapter protein linking nNOS to specific targets, such as Dexras1 and the synapsins. Alternative splicing results in multiple transcript variants encoding different isoforms.

    Alias Symbols: 6330408P19Rik, CAPON

    Protein Interaction Partner: LRP1,LRP2,NOS1,RASD1,SYN1,SYN2,SYN3,LRP1,LRP2,LRP8,NOS1,RASD1,SYN1,SYN2,SYN3

    Protein Size: 586
    Molecular Weight
    63 kDa
    Gene ID
    9722
    NCBI Accession
    NM_001126060
    UniProt
    O75052
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