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NAD(P)H Dehydrogenase, Quinone 1 (NQO1) (Middle Region) Peptide

NQO1 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN980861
  • Target See all NQO1 products
    NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 7
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    AILKGWFERV FIGEFAYTYA AMYDKGPFRS KKAVLSITTG GSGSMYSLQG
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-NQO1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))
    Synonyms
    zgc:77191 Peptide, wu:fb63c10 Peptide, nqo1 Peptide, DHQU Peptide, DIA4 Peptide, DTD Peptide, NMOR1 Peptide, NMORI Peptide, QR1 Peptide, Dia4 Peptide, AV001255 Peptide, Dtd Peptide, Nmo-1 Peptide, Nmo1 Peptide, Nmor1 Peptide, Ox-1 Peptide, Ox1 Peptide, Qr1 Peptide, NADPH-d Peptide, NAD(P)H dehydrogenase, quinone 1 Peptide, NAD(P)H quinone dehydrogenase 1 Peptide, NAD(P)H dehydrogenase, quinone 1 L homeolog Peptide, nqo1 Peptide, NQO1 Peptide, Bpet2092 Peptide, nqo1.L Peptide, Nqo1 Peptide
    Background
    This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

    Alias Symbols: DHQU, DIA4, DTD, NMOR1, NMORI, QR1

    Protein Interaction Partner: DNAJB1,HSPA1A,NQO1,TP53,HSPA4,ING1,NQO1

    Protein Size: 274
    Molecular Weight
    31 kDa
    Gene ID
    1728
    NCBI Accession
    NM_000903, NP_000894
    UniProt
    P15559
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