Origin Recognition Complex, Subunit 3 (ORC3) (C-Term) Peptide
ORC3
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN981199
Quick Overview for Origin Recognition Complex, Subunit 3 (ORC3) (C-Term) Peptide (ABIN981199)
Target
ORC3
(Origin Recognition Complex, Subunit 3 (ORC3))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- VVTAAEKMDA NSATSEEMNE IIHARFIRAV SELELLGFIK PTKQKTDHVA
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-ORC3L Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Origin Recognition Complex, Subunit 3 (ORC3) peptide
ORC3 Reactivity: Human, Cow, Dog, Mouse, Rat Host: Synthetic BP, Imm
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ORC3 (Origin Recognition Complex, Subunit 3 (ORC3))
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Background
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The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Studies of a similar gene in Drosophila suggested a possible role of this protein in neuronal proliferation and olfactory memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene.
Alias Symbols: LAT, LATHEO, ORC3, ORC3L
Protein Interaction Partner: CCNE2,CDC45,CDC6,CDK4,DBF4,MCM10,MCM5,MCM7,ORC1,ORC2,ORC3,ORC4,ORC5,ORC6,BRCA1,MCM4,MCM7,ORC2,ORC4,ORC5,ORC6,TERF2
Protein Size: 712 -
Molecular Weight
- 82 kDa
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Gene ID
- 23595
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NCBI Accession
- NM_181837, NP_862820
Target
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