Origin Recognition Complex, Subunit 3 (ORC3) (N-Term) Peptide
ORC3
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all ORC3 products
- ORC3 (Origin Recognition Complex, Subunit 3 (ORC3))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- RFETYQLIWQ QMKSENERLQ EELNKNLFDN LIEFLQKSHS GFQKNSRDLG
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-ORC3L Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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Origin Recognition Complex, Subunit 3 (ORC3) peptide
ORC3 Reactivity: Human, Cow, Dog, Mouse, Rat Host: Synthetic BP, Imm
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ORC3 (Origin Recognition Complex, Subunit 3 (ORC3))
- Synonyms
- CG4088 Peptide, DmORC3 Peptide, DmOrc3 Peptide, Dmel\\CG4088 Peptide, LAT Peptide, ORC Peptide, ORC3 Peptide, Orc3 Peptide, l(2)49Fd Peptide, l(2)vr6 Peptide, vr-6 Peptide, vr6 Peptide, ORC3L Peptide, orc3 Peptide, ATORC3 Peptide, F5E19.30 Peptide, F5E19_30 Peptide, ORIGIN RECOGNITION COMPLEX SUBUNIT 3 Peptide, origin recognition complex subunit 3 Peptide, Afu8g04240 Peptide, DDBDRAFT_0216767 Peptide, DDBDRAFT_0233773 Peptide, DDB_0216767 Peptide, DDB_0233773 Peptide, LOC100226325 Peptide, LATHEO Peptide, Orc3l Peptide, Origin recognition complex subunit 3 Peptide, origin recognition complex subunit 3 Peptide, origin recognition complex, subunit 3 Peptide, Orc3 Peptide, ORC3 Peptide, orc3 Peptide, AFUA_8G04240 Peptide, BDBG_01002 Peptide, orcC Peptide
- Background
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The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Studies of a similar gene in Drosophila suggested a possible role of this protein in neuronal proliferation and olfactory memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene.
Alias Symbols: LAT, LATHEO, ORC3, ORC3L
Protein Interaction Partner: CCNE2,CDC45,CDC6,CDK4,DBF4,MCM10,MCM5,MCM7,ORC1,ORC2,ORC3,ORC4,ORC5,ORC6,BRCA1,MCM4,MCM7,ORC2,ORC4,ORC5,ORC6,TERF2
Protein Size: 712 - Molecular Weight
- 82 kDa
- Gene ID
- 23595
- NCBI Accession
- NM_181837, NP_862820
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