Par-6 Partitioning Defective 6 Homolog alpha (PARD6A) (N-Term) Peptide
PARD6A
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all PARD6A products
- PARD6A (Par-6 Partitioning Defective 6 Homolog alpha (PARD6A))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- MARPQRTPAR SPDSIVEVKS KFDAEFRRFA LPRASVSGFQ EFSRLLRAVH
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PARD6A Antibody(ARP42883_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PARD6A (Par-6 Partitioning Defective 6 Homolog alpha (PARD6A))
- Synonyms
- PARD6A Peptide, 0710008C04Rik Peptide, 2610010A15Rik Peptide, PAR6alpha Peptide, Par-6 Peptide, Par6 Peptide, Par6c Peptide, TAX40 Peptide, Tip-40 Peptide, Par-6a Peptide, Par6a Peptide, PAR-6A Peptide, PAR6 Peptide, PAR6C Peptide, TIP-40 Peptide, par-6 partitioning defective 6 homolog alpha (C. elegans) Peptide, par-6 family cell polarity regulator alpha Peptide, Partitioning defective protein 6 Peptide, PARD6A Peptide, Pard6a Peptide, par-6 Peptide
- Background
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This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: PAR-6A, PAR6, PAR6C, PAR6alpha, TAX40, TIP-40
Protein Interaction Partner: PLCB1,PLCB3,CDC42,CDH5,CRB3,ECT2,GLS,MAP2K5,MARK2,MARK4,PARD3,PARD6B,PLCB1,PLCB3,PRKCG,PRKCH,PRKCI,PRKCZ,RAC1,RHOQ,TCP10,TGFBR1,YWHAH,YWHAZ,CDC42,DGKZ,ECT2,MPP5,PARD3,PRKCI,PRKCZ,RAC1,RHOQ
Protein Size: 345 - Molecular Weight
- 37 kDa
- Gene ID
- 50855
- NCBI Accession
- NM_001037281, NP_001032358
- UniProt
- Q3TY70
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