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Parkinson Protein 7 (PARK7) (C-Term) Peptide

PARK7 Reactivity: Human Host: Synthetic BP, IHC, WB
Catalog No. ABIN981353
  • Target See all PARK7/DJ1 (PARK7) products
    PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))
    Protein Region
    C-Term
    Origin
    Human
    Source
    • 5
    Synthetic
    Application
    Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-PARK7 antibody (Catalog #: ARP51267_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))
    Synonyms
    DJ-1 Peptide, DJ1 Peptide, CAP1 Peptide, Dj1 Peptide, SP22 Peptide, dj1 Peptide, zgc:103725 Peptide, park7b Peptide, park7 Peptide, park7a Peptide, Parkinsonism associated deglycase Peptide, Parkinson disease (autosomal recessive, early onset) 7 Peptide, parkinson protein 7 Peptide, parkinson protein 7 S homeolog Peptide, parkinson protein 7 L homeolog Peptide, PARK7 Peptide, Park7 Peptide, park7 Peptide, park7.S Peptide, park7.L Peptide
    Background
    PARK7 belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7.The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene.

    Alias Symbols: DJ-1, DJ1, FLJ27376

    Protein Interaction Partner: DAXX,EFCAB6,PARK7,PIAS2,PPP2R1A,PPP2R1B,SUMO1,C19orf62,EFCAB6,PIAS2,USP19

    Protein Size: 189
    Molecular Weight
    20 kDa
    Gene ID
    11315
    NCBI Accession
    NM_007262, NP_009193
    UniProt
    Q99497
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