(1 reference)-
- Target See all PAX7 products
- PAX7 (Paired Box 7 (PAX7))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- QADFSISPLH GGLDSATSIS ASCSQRADSI KPGDSLPTSQ AYCPPTYSTT
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PAX7 antibody (Catalog #: ARP32742_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
-
-
- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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-
: "Klotho gene silencing promotes pathology in the mdx mouse model of Duchenne muscular dystrophy." in: Human molecular genetics, Vol. 25, Issue 12, pp. 2465-2482, (2016) (PubMed).
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: "Klotho gene silencing promotes pathology in the mdx mouse model of Duchenne muscular dystrophy." in: Human molecular genetics, Vol. 25, Issue 12, pp. 2465-2482, (2016) (PubMed).
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- Target
- PAX7 (Paired Box 7 (PAX7))
- Synonyms
- PAX7 Peptide, HUP1 Peptide, PAX7B Peptide, RMS2 Peptide, pax-7 Peptide, PAX-7 Peptide, RGD1564360 Peptide, Pax-7 Peptide, pax7 Peptide, pax7c Peptide, pax7d Peptide, pax7e Peptide, paired box 7 Peptide, paired box protein Pax-7 Peptide, paired box 7 L homeolog Peptide, paired box 7a Peptide, PAX7 Peptide, pax7.L Peptide, LOC536229 Peptide, Pax7 Peptide, pax7a Peptide
- Background
-
PAX7 is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box gene 7 is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Alternative splicing in this gene has produced two known products but the biological significance of the variants is unknown.
Alias Symbols: FLJ37460, HUP1, PAX7B, RMS2
Protein Interaction Partner: HIRA,UBC,Ubc
Protein Size: 520 - Molecular Weight
- 57 kDa
- Gene ID
- 5081
- NCBI Accession
- NM_002584, NP_002575
- UniProt
- P23759
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