phosphodiesterase 4B, cAMP-Specific (PDE4B) (Middle Region) Peptide
PDE4B
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all PDE4B products
- PDE4B (phosphodiesterase 4B, cAMP-Specific (PDE4B))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PDE4B antibody (Catalog #: ARP56256_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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phosphodiesterase 4B, cAMP-Specific (PDE4B) peptide
PDE4B Reactivity: Human, Mouse, Rat Host: Synthetic BP, Imm
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PDE4B (phosphodiesterase 4B, cAMP-Specific (PDE4B))
- Synonyms
- dpde4 Peptide, pde4b5 Peptide, pdeivb Peptide, Dpde4 Peptide, R74983 Peptide, dunce Peptide, PDE4/IVb Peptide, Pde4B1 Peptide, Pde4B2 Peptide, Pde4B3 Peptide, Pde4B4 Peptide, DPDE4 Peptide, PDE4B5 Peptide, PDEIVB Peptide, phosphodiesterase 4B Peptide, phosphodiesterase 4B, cAMP specific Peptide, phosphodiesterase 4B S homeolog Peptide, pde4b Peptide, PDE4B Peptide, Pde4b Peptide, pde4b.S Peptide
- Background
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The specific function of this protein remains unknown.This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: DKFZp686F2182, DPDE4, MGC126529, PDE4B5, PDEIVB
Protein Interaction Partner: PRKACA
Protein Size: 564 - Molecular Weight
- 64 kDa
- Gene ID
- 5142
- NCBI Accession
- NM_001037339, NP_001032416
- UniProt
- Q5TEK5
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