phosphodiesterase 5A, cGMP-Specific (PDE5A) (C-Term) Peptide

Details for Product No. ABIN981513, Supplier: Log in to see
Protein Name
  • CGB-PDE
  • CN5A
  • PDE5
  • PDE5A2
  • Cgbpde
  • Cn5n
  • Pde5
  • Pde5a1
  • PDE5A
  • pde5a
  • cgb-pde
  • cn5a
  • pde5
  • pde5a1
  • phosphodiesterase 5A
  • phosphodiesterase 5A, cGMP-specific
  • phosphodiesterase 5A S homeolog
  • phosphodiesterase 5A, cGMP-specific, b
  • PDE5A
  • Pde5a
  • pde5a.S
  • pde5ab
  • pde5a
Protein Region
C-Term
Origin
Human
6
2
2
2
1
1
1
Source
Synthetic
Application
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
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Blocked Antibody anti-phosphodiesterase 5A, cGMP-Specific (PDE5A) (C-Term) antibody (ABIN2789423)
Sequence TACDLSAITK PWPIQQRIAE LVATEFFDQG DRERKELNIE PTDLMNREKK
Characteristics This is a synthetic peptide designed for use in combination with anti-PDE5A Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Purification Purified
Background This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms.

Alias Symbols: CGB-PDE, CN5A, PDE5, PDE5A1

Protein Interaction Partner: CASP3,PRKG1

Protein Size: 823
Molecular Weight 93 kDa
Gene ID 8654
NCBI Accession NM_033437, NP_246273
UniProt O76074
Application Notes Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Concentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.