Paternally Expressed 3 (PEG3) Peptide
PEG3
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all PEG3 products
- PEG3 (Paternally Expressed 3 (PEG3))
- Origin
- Human
- Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PEG3 antibody (Catalog #: ARP38756_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PEG3 (Paternally Expressed 3 (PEG3))
- Synonyms
- PW1 Peptide, ZKSCAN22 Peptide, ZNF904 Peptide, ZSCAN24 Peptide, AL022617 Peptide, ASF-1 Peptide, End4 Peptide, Gcap4 Peptide, Pw1 Peptide, Zfp102 Peptide, mKIAA0287 Peptide, PEG3 Peptide, paternally expressed 3 Peptide, paternally-expressed gene 3 protein Peptide, PEG3 Peptide, Peg3 Peptide, LOC100448879 Peptide
- Background
-
PEG3 induces apoptosis in cooperation with SIAH1A and acts as a mediator between TP53/p53 and BAX in a neuronal death pathway that is activated by DNA damage. PEG3 acts synergistically with TRAF2 and inhibits TNF induced apoptosis through activation of NF-kappa-B. PEG3 also possesses a tumor suppressing activity in glioma cells.
Alias Symbols: PW1, ZNF904, ZSCAN24
Protein Interaction Partner: SIAH1,SIAH2,TRAF2,USP7,BRCA1,SIAH1,SIAH2
Protein Size: 1588 - Molecular Weight
- 181 kDa
- Gene ID
- 5178
- NCBI Accession
- NM_006210, NP_006201
- UniProt
- Q9GZU2
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