Phytanoyl-CoA 2-Hydroxylase (PHYH) (N-Term) Peptide
PHYH
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN981712
Quick Overview for Phytanoyl-CoA 2-Hydroxylase (PHYH) (N-Term) Peptide (ABIN981712)
Target
PHYH
(Phytanoyl-CoA 2-Hydroxylase (PHYH))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- TLPEILKYVE CFTGPNIMAM HTMLINKPPD SGKKTSRHPL HQDLHYFPFR
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-PHYH Antibody(ARP56681_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PHYH (Phytanoyl-CoA 2-Hydroxylase (PHYH))
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Background
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This gene is a member of the PhyH family and encodes a peroxisomal protein that is involved in the alpha-oxidation of 3-methyl branched fatty acids. Specifically, this protein converts phytanoyl-CoA to 2-hydroxyphytanoyl-CoA. Mutations in this gene have been associated with Refsum disease (RD) and deficient protein activity has been associated with Zellweger syndrome and rhizomelic chondrodysplasia punctata. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: LN1, LNAP1, PAHX, PHYH1, RD
Protein Interaction Partner: ACSL6,F8,FKBP4,MAGEA11,PEX7,PHYH,PHYHIP,TOM1L1,COPS3,F8,FKBP4,MAGEA11,PEX7,TOM1L1,WDR8
Protein Size: 238 -
Molecular Weight
- 26 kDa
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Gene ID
- 5264
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NCBI Accession
- NM_001037537, NP_001032626
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UniProt
- O14832
Target
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